I was in WDW solo for 3 days and had a BLAST! haha. It really depends on your outlook & mood though, just keep positive & have fun. If you start to THINK "Man, this is the pits being here alone," then guess what... you WILL make it 'the pits.' It's great that you have family close by so they can join you on the nicer dinners. On the nights you have to eat dinner alone, if you feel too uncomfortable eating table service, thank goodness Disneyland has some of the best counter service locations; French Market, Rancho Del Zocalo, Pacific Wharf Cafe, La Brea, etc. You wouldn't feel uncomfortable at any of those.
It REALLY stinks your wife can't go
I had the advantage of being in WDW where more than several Mousebuzzers wanted to keep me company which was awesome but that may not be as easy in DL. Either way, you seem like a pretty laid-back friendly guy who should be able to ease through it no problem; focus on doing lots of photography, make CMs your bestest friends in the world, and do whatever in the heck you want!